Key result
Initial electrocardiogram variables (sum of absolute ST deviation) and maximum creatine kinase levels, along with prior MI and diabetes, were associated with LVEF ≤ 40% (observed in 44.4%).
Why the study?
Do initial ECG variables and creatine kinase levels predict left ventricular dysfunction (LVEF ≤ 40%) in patients with acute STEMI?
Observational (n=124)
No
Do initial ECG variables and creatine kinase levels predict left ventricular dysfunction (LVEF ≤ 40%) in patients with acute STEMI?
Initial ECG variables (sum of absolute ST deviation) and maximum CK levels are useful predictors of left ventricular dysfunction (LVEF ≤ 40%) in patients with acute STEMI.
Aim: Our aim was to determine the clinical, electrocardiographic (ECG) and biochemical predictors of left ventricular dysfunction in patients with acute ST elevation myocardial infarction (STEMI). Methods: Patients with STEMI admitted in Loghman Hakim hospital were studied. The ECG variables were: ECG rate, ECG rhythm, QRS duration, sum of absolute ST deviation (in all, inferior and anterior leads), number of leads with ST elevation, maximum ST elevation, presence of pathological Q waves and location of the infarct. The primary outcome measure was LVEF ≤ 40%. Results: A total of 124 patients (91 male, 33 female) were studied. Mean age of the patients was 59.1 years (SD=12.6). Of these, 52 patients (44.4%) had an LVEF ≤ 40% and angiography was recommended to 68 patients (54.8%) at the time of discharge. The multivariate analysis showed an association of LVEF ≤ 40% with prior MI, diabetes, maximum creatine kinase (CK) levels, the sum of absolute ST deviation in all and inferior leads. Conclusions: The initial ECG and CK levels in patients with STEMI may contain valuable information for risk stratification, determination of prognosis and the subsequent management plan. The results of this study warrant further studies to define patients who benefit most from invasive and sophisticated interventions.
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Nourian et al. (2016) conducted an observational in acute ST elevation myocardial infarction (STEMI) (n=124). Initial electrocardiogram and creatine kinase levels was evaluated on LVEF ≤ 40%. Initial electrocardiogram variables (sum of absolute ST deviation) and maximum creatine kinase levels, along with prior MI and diabetes, were associated with LVEF ≤ 40% (observed in 44.4%).
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