Key result
Patients presenting with acute myocarditis and life-threatening arrhythmias had a nearly sevenfold higher risk of adverse events compared to those presenting with chest pain (HR 6.97).
Why the study?
Acute myocarditis is a heterogeneous condition with variable survival estimates, prompting an assessment of demographic characteristics and long-term outcomes using non-invasive diagnostic criteria.
Population
199 patients with CMR-confirmed acute myocarditis
Comparison
Clinical presentations and demographic factors including sex and ethnicity
Design
Cohort study
Follow-up
Median 53 (IQR 34–76) months
Authors
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Low event rates support conservative management for most; leaves open arrhythmia-based risk stratification pending prospective validation.
Cohort (n=199)
No
Hazard Ratio: 6.97 (95% CI 1.87–26)
p-value: p=0.004
Cannatà et al. (2022) conducted a cohort in Acute myocarditis (n=199). Arrhythmia presentation vs. Chest pain presentation was evaluated on Composite of all-cause mortality, resuscitated cardiac arrest, and appropriate implantable cardioverter defibrillator (ICD) therapy (HR 6.97, 95% CI 1.87-26.00, p=0.004). Patients presenting with acute myocarditis and life-threatening arrhythmias had a nearly sevenfold higher risk of adverse events compared to those presenting with chest pain (HR 6.97).
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