Key result
Electrogram-gated pulsed radiofrequency ablation created significantly deeper lesions than conventional ablation at 9-mm lateral sliding distances (4.41 vs 2.94 mm; P<<0.001).
Why the study?
Does electrogram-gated pulsed power ablation improve lesion depth compared to conventional ablation in a myocardial phantom model with lateral catheter sliding?
Population
Thermochromic gel myocardial phantom (n=48 radiofrequency ablations)
Comparison
Electrogram-gated pulsed power ablation at 20%… vs Conventional 30 W ablation with lateral sliding…
Design
Preclinical, Ablation settings were randomized
Authors
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Electrogram-gated ablation may yield deeper lesions in vitro; leaves open clinical translation pending in vivo trials.
RCT (n=48)
randomized
Does electrogram-gated pulsed power ablation improve lesion depth compared to conventional ablation in a myocardial phantom model with lateral catheter sliding?
Absolute Event Rate: 4.41% vs 2.94%
p-value: p=<<0.001
Electrogram-gated pulsed radiofrequency delivery negates the effects of lateral catheter movement, creating consistently deeper lesions faster than conventional ablation in a phantom model.
Chik et al. (2014) reported an RCT. Electrogram-gated pulsed power ablation vs. Conventional (nongated) 30 W ablation was evaluated on Lesion depth at 9-mm lateral sliding distance (p=<<0.001). Electrogram-gated pulsed radiofrequency ablation created significantly deeper lesions than conventional ablation at 9-mm lateral sliding distances (4.41 vs 2.94 mm; P<<0.001).
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