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This review aims to summarize the pharmacological significance and therapeutic potential of coumarin derivatives.

July 1, 2026Open Access

A Comprehensive Review on Pharmacological Importance of Coumarin and Its Derivatives

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Comprehensive review demonstrates coumarins’ diverse pharmacological properties, suggesting potential for drug development.

This review aims to summarize the pharmacological significance and therapeutic potential of coumarin derivatives.
Reviewed literature on coumarin pharmacological properties and applications.
Discussed synthetic methods including eco-friendly techniques and microwave-assisted synthesis.
Highlighted computational approaches for drug candidate optimization.
Coumarins exhibit significant antioxidant, antimicrobial, and anticancer activities attributed to their chemical structure.
Recent synthetic advancements have improved the biological activity and selectivity of coumarin derivatives.
Computational techniques have facilitated rapid identification of potential drug candidates, despite challenges like low solubility.

1*K. Laxmiprasanna, 2K. Soumya, 3K. Rajkumar Reddy, 4K. Nishiekanth, 5Mohd Afroz and 6V. Vasudha (2026) studied this question.

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