Efficacy of NMRT on Intra Vertebral Disc Prolapse, With Pain Ranging From Mild to Severe With or Without Impending Neurological Damage: Original Research

Background: Chronic low back pain (LBP) is a prevalent and disabling condition frequently associated with intervertebral Disc Degeneration (DD), although imaging findings often poorly correlate with symptoms. Emerging biophysical therapies such as Nuclear Magnetic Resonance Therapy (NMRT) aim to modulate cellular activity and promote tissue repair. Objective: To evaluate the clinical efficacy of targeted NMRT (tNMR) in 150 patients with chronic LBP associated with Disc Degeneration. Methods: This prospective, clinical trial was conducted at a tertiary Orthopaedic centre in Bengaluru. Patients with clinically and radiologically confirmed disc pathology were enrolled and allocated to the tNMR treatment group. All participants received standardized polymodular non-surgical therapy. Clinical outcomes were assessed using validated measures of pain and functional disability, while structural changes were evaluated through MRI. Results: Patients receiving tNMR demonstrated significant improvement in pain reduction and functional outcomes compared to baseline. MRI findings suggested favourable structural changes in intervertebral disc morphology. The intervention was well tolerated with no major adverse effects. Conclusion: Targeted NMRT appears to be a safe and effective non-invasive modality for managing chronic LBP associated with disc degeneration, offering potential benefits in both symptomatic relief and structural recovery.