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July 1, 2026Pest Management Science

A pH ‐responsive vanillin‐Schiff base microcapsule for controlled release of pyraclostrobin

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Authors

WWWenneng WuCYChang YanGPG H Peng

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Overview

Randomized trial evaluates antifungal effects of pH-responsive microcapsules in agriculture, indicating promising applications for sustainable pest management.

Key Points

  • This research aims to develop a pH-responsive microcapsule for the controlled release of pyraclostrobin, a pesticide.
  • Fabricated microcapsules (Pyr@PU) using interfacial polymerization with isocyanate core and vanillin-Schiff base shell.
  • Conducted in vitro release experiments to assess the responsiveness to pH levels and quantified drug loading and encapsulation efficiency.
  • Performed bioactivity assays to evaluate antifungal effects and toxicity assessments on zebrafish and rice seeds.
  • The microcapsules achieved a loading capacity of 80.89% and encapsulation efficiency of 96.17%.
  • At pH 4.0, cumulative release after 144 hours was 82.81%.
  • Pyr@PU exhibited antifungal efficacy with protective (79.62%) and curative (67.59%) effects on kiwifruit pathogens at 200 μg mL−1.

Cite This Study

Wu et al. (2026) studied this question.

synapsesocial.com/papers/6a44af055cd2549c8bc440ebhttps://doi.org/10.1002/ps.71054
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