What question did this study set out to answer?

This research aims to evaluate the effectiveness of multiparametric fMRI techniques in detecting early renal allograft dysfunction after kidney transplantation.

July 1, 2026BMC NephrologyOpen Access

Multiparametric functional MRI for detection of early renal allograft dysfunction after kidney transplantation: a systematic review and meta-analysis

View Full Paper

Ask AI

Bookmark

Authors

YJYi-Zhu JiangChinese Academy of Medical Sciences & Peking Union Medical College RWRui WangKing University TSTao SuChinese Academy of Medical Sciences & Peking Union Medical College

Discussion

Member takes

Implication

Systematic review reveals fMRI techniques effectively detect early allograft dysfunction in kidney transplant recipients, indicating further research is needed.

Key Points

This research aims to evaluate the effectiveness of multiparametric fMRI techniques in detecting early renal allograft dysfunction after kidney transplantation.
Systematic search across multiple databases (PubMed, Web of Science, etc.) for relevant studies.
Quality appraisal using QUADAS-2 and data pooling with random-effects models.
Subgroup analyses were conducted based on magnetic field strength, post-transplant time, and baseline creatinine.
ASL-derived cortical renal blood flow discriminated normal from impaired renal function (MD 98.48 mL·min⁻¹·100 g⁻¹, 95% CI 68.66-128.31; P < 0.00001; I²=57%).
BOLD MRI identified acute rejection but not acute tubular necrosis (lower R2*; I²=77–86%).
IVIM-derived D values showed strong discriminatory power (MD 0.14–0.16 × 10⁻³ mm²/s; P < 0.00001; I²=0%).

Cite This Study

Jiang et al. (2026) studied this question.

synapsesocial.com/papers/6a44af635cd2549c8bc4451a https://doi.org/10.1186/s12882-026-05154-y

View Full Paper

Ask AI

Bookmark

Implication

Systematic review reveals fMRI techniques effectively detect early allograft dysfunction in kidney transplant recipients, indicating further research is needed.

Multiparametric functional MRI for detection of early renal allograft dysfunction after kidney transplantation: a systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Multiparametric functional MRI for detection of early renal allograft dysfunction after kidney transplantation: a systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider