The present review focuses on the green synthesis of Zinc Oxide nanoparticles (ZnO-NPs) using Aloe vera leaf extract. It also discusses their potential pharmaceutical, cosmetic, and biomedical applications. Nanotechnology has gained significant importance due to the unique physicochemical properties of nanoparticles, such as high surface area, enhanced reactivity, antimicrobial activity, and UV protection ability. ZnO nanoparticles are widely used in sunscreens, wound healing products, drug delivery systems, and antimicrobial formulations because of their excellent antibacterial, antioxidant, anti-inflammatory, and photocatalytic properties. Conventional synthesis methods involve toxic chemicals and high energy consumption. In contrast, green synthesis using plant extracts offers an eco-friendly, economical, and safe alternative. Aloe vera contains bioactive phytochemicals, including flavonoids, phenolic compounds, polysaccharides, and proteins. These compounds act as natural reducing and stabilizing agents during nanoparticle synthesis. The synthesized ZnO nanoparticles were characterized using UV-Visible spectroscopy, XRD, FTIR, and SEM analysis to determine their optical, crystalline, and morphological properties. The study also highlights the strong UV-blocking ability of ZnO nanoparticles, making them suitable for sunscreen and cosmetic formulations. Overall, green synthesized ZnO nanoparticles exhibit promising applications in pharmaceutical, biomedical, environmental, and cosmetic fields due to their stability, biocompatibility, and environmentally friendly nature.
Pranay S. Mowade*, Rohini S. Malikar, Asst. Prof. Shailaja W. Gawande, Prof. Dr. Manisha D. Kitukale (Wed,) studied this question.