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July 1, 2026Critical Reviews in Toxicology

Inhalation exposure and health effects of copper particles in the context of occupational exposure limit derivation

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Authors

CPCraig A. PolandAOAdriana R. OllerLLLen Levy

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Overview

Review examines inhalation toxicity and health effects of copper in workers, suggesting updated exposure limits.

Key Points

  • This review aims to evaluate the inhalation toxicity of copper and derive an updated occupational exposure limit.
  • Examined recent data on health effects of copper inhalation in exposed workforces.
  • Characterized copper forms in smelters during inhalation exposure.
  • Used a dosimetric model to translate points of departure for humans.
  • Identified toxicological mode of action and respiratory effects in animal models.
  • Showed rapid clearance of copper from the lung in models analyzed.
  • Discussed chemical-specific assessment factors to address uncertainties in exposure levels.

Cite This Study

Poland et al. (2026) studied this question.

synapsesocial.com/papers/6a44af635cd2549c8bc44606https://doi.org/10.1080/10408444.2026.2684936
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