Key result
Heparin shows no proven benefit for preventing restenosis after coronary angioplasty.
Why the study?
Restenosis after coronary angioplasty remains a significant problem, and while experimental work suggests heparin may inhibit smooth muscle cell proliferation, limited clinical studies have failed to show therapeutic efficacy.
Does heparin prevent restenosis after coronary angioplasty?
Population
Patients undergoing coronary angioplasty
Design
Review
Authors
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Current evidence does not support heparin to prevent restenosis after angioplasty; leaves open need for rigorous trials reconciling experimental promise with clinical results.
Does heparin prevent restenosis after coronary angioplasty?
While experimental models suggest heparin may prevent restenosis after angioplasty, clinical evidence is lacking, highlighting the need for appropriate clinical trials.
More et al. (1993) conducted a review in Restenosis following coronary angioplasty. Heparin was evaluated on Restenosis. Heparin use after coronary angioplasty lacks proven therapeutic efficacy for preventing restenosis in clinical studies to date, despite promising experimental models.
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