Key result
Pharmacological therapies evaluated over the past decade have not successfully reduced the 30-50% incidence of restenosis after angioplasty, prompting new approaches like local drug delivery.
Population
Patients undergoing angioplasty
Design
Review
Authors
Discussion
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Member takes
Implication
Systemic therapies remain unproven for restenosis; leaves open whether local delivery approaches will prove effective in trials.
Structured PICO
P
Population
Patients undergoing angioplasty
I
Intervention
Pharmacological therapies to prevent restenosis (including combination drug therapy, local delivery, and gene therapy)
O
Outcome
Restenosis
As of 1993, no systemic pharmacological therapy had proven successful in preventing restenosis after angioplasty, prompting a shift toward local delivery and combination therapies.
Cite This Study
David P. Faxon (1993) conducted a review in Restenosis after angioplasty. Pharmacological therapies was evaluated. Pharmacological therapies evaluated over the past decade have not successfully reduced the 30-50% incidence of restenosis after angioplasty, prompting new approaches like local drug delivery.