Key result
Verapamil suppresses exercise-recovery premature ventricular complexes and prevents ventricular tachycardia in adolescent males.
Why the study?
Only a few small case series have reported idiopathic ventricular tachycardia in the pediatric population, making its true prevalence in this age group difficult to determine.
Case Report (n=3)
Supports verapamil for exercise-recovery VT in adolescents with normal hearts; extends limited pediatric RCT evidence beyond adult cohorts.
Idiopathic ventricular tachycardias (VT) occur in the absence of structural heart disease, which includes previous myocardial infarction, cardiomyopathy, and congenital heart disease. They can originate from the conduction system or from other focal sources in the myocardium, most commonly the left ventricular outflow tract and the right ventricular outflow tract (RVOT).1 Idiopathic VTs usually manifest between the third and fifth decades of life, and only a few small case series have reported the arrhythmia in the pediatric population, making it difficult to determine the true prevalence within this age group.
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Li et al. (2020) conducted a case report in Idiopathic ventricular tachycardia / Intermediate-coupled premature ventricular complexes (n=3). Verapamil was evaluated on Suppression of ventricular arrhythmias on repeat exercise stress testing. Verapamil successfully suppressed intermediate-coupled premature ventricular complexes and prevented ventricular tachycardia during exercise recovery in three adolescent males with normal hearts.
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