What is the clinical evidence from this study?

Study design: Case Report. Population: Idiopathic ventricular fibrillation (n=1). Intervention: Radiofrequency catheter ablation. Primary outcome: Recurrence of ventricular fibrillation or ICD shock.

July 1, 2001HeartOpen Access

Catheter ablation of a monofocal premature ventricular complex triggering idiopathic ventricular fibrillation

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Key result

Radiofrequency catheter ablation successfully eradicated the monofocal premature ventricular complexes triggering idiopathic ventricular fibrillation, with no recurrence of ventricular fibrillation or ICD shocks over 20 months.

Why the study?

Does radiofrequency catheter ablation prevent ventricular fibrillation in a patient with idiopathic ventricular fibrillation triggered by a monofocal premature ventricular complex?

Population

n=1, 62-year-old man with recurrent syncope, frequent repetitive premature ventricular complexes of right…

Design

Case_report

Follow-up

20 months

Authors

STSeiji TakatsukiKeio University

Discussion

Member takes

Implication

May support PVC-trigger ablation in idiopathic VF; leaves open validation in prospective trials.

Key Points

To investigate the effectiveness of catheter ablation in a patient with idiopathic ventricular fibrillation triggered by a premature ventricular complex.
Patient presented with recurrent syncope and was diagnosed with idiopathic ventricular fibrillation.
Electrophysiological study confirmed the premature ventricular complex as the trigger.
Radiofrequency catheter ablation was performed to eliminate the triggering premature ventricular complex.
Post-ablation, no episodes of ventricular fibrillation were reported.
The patient no longer required an implanted cardioverter-defibrillator for recurrent events.
Improvement was observed with no necessity for drug treatment after the procedure.

Study Design

Type

Case Report (n=1)

Multicenter

Structured PICO

Does radiofrequency catheter ablation prevent ventricular fibrillation in a patient with idiopathic ventricular fibrillation triggered by a monofocal premature ventricular complex?

Population

A 62-year-old man with idiopathic ventricular fibrillation triggered by monofocal premature ventricular complexes from the right ventricular outflow tract, followed for 20 months after ablation.

Intervention

Radiofrequency catheter ablation targeting the focus in the right ventricular outflow tract.

Outcome

Recurrence of ventricular fibrillation or shock delivery from the ICD.hard clinical

Catheter ablation targeting a culprit premature ventricular complex of monofocal origin may be an effective option for preventing the recurrence of idiopathic ventricular fibrillation.

Limitations

Uncertain whether the intervention only eliminated a trigger for ventricular fibrillation or whether it ablated a common arrhythmogenic site.
The substrate for ventricular fibrillation may still be present, requiring continued ICD backup.
Single case report limits generalizability.
Uncertain whether intervention only eliminated a trigger or ablated a common arrhythmogenic site
Substrate for ventricular fibrillation may still be present, meaning an ICD may remain necessary

Cite This Study

Seiji Takatsuki (2001) conducted a case report in Idiopathic ventricular fibrillation (n=1). Radiofrequency catheter ablation was evaluated on Recurrence of ventricular fibrillation or ICD shock. Radiofrequency catheter ablation successfully eradicated the monofocal premature ventricular complexes triggering idiopathic ventricular fibrillation, with no recurrence of ventricular fibrillation or ICD shocks over 20 months.

synapsesocial.com/papers/6a45acc76f4bbfd563da3056 https://doi.org/10.1136/heart.86.1.e3

Topics

Cardiac device therapy AF ablation outcomes

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Catheter ablation of a monofocal premature ventricular complex triggering idiopathic ventricular fibrillation

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Limitations

Cite This Study

Topics

Catheter ablation of a monofocal premature ventricular complex triggering idiopathic ventricular fibrillation

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

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