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February 1, 2015Hormone Molecular Biology and Clinical Investigation

Visceral adiposopathy: a vascular perspective

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Key result

Visceral adiposopathy and dysfunctional adipose tissue up-regulate pro-inflammatory mediators, contributing to vascular abnormalities and obesity-related cardiovascular disease.

Population

Obese individuals with central adiposity and visceral fat deposition

Design

Review

Authors

MFMelissa G. FarbBoston UniversityNGNoyan GokceCardiac Imaging

Discussion

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Implication

Visceral adiposity may impair endothelial function in obesity; hypothesis-generating for targeted cardiometabolic therapies.

Structured PICO

P
Population
Obese individuals with central adiposity and visceral fat deposition

Visceral adiposopathy contributes to obesity-related cardiovascular disease through systemic pro-inflammatory and pro-atherosclerotic vascular changes.

Cite This Study

Farb et al. (2015) conducted a review in Obesity and cardiometabolic disease. Visceral adiposopathy was evaluated. Visceral adiposopathy and dysfunctional adipose tissue up-regulate pro-inflammatory mediators, contributing to vascular abnormalities and obesity-related cardiovascular disease.

synapsesocial.com/papers/6a45ad3e6f4bbfd563da3106https://doi.org/10.1515/hmbci-2014-0047
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