Investigates tear cytokine levels and their clinical correlations in chronic ocular GvHD, suggesting potential biomarkers for severity.
Chronic ocular graft-versus-host disease (GvHD) complicates allogeneic stem cell transplantation, with immune-mediated inflammation and fibrosis of the ocular surface leading to severe dry eye disease (DED). While previous studies have demonstrated elevated tear cytokines in chronic ocular GvHD, few have characterised early-stage cytokine correlations with clinical severity [ 1 , 2 , 3 ].
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Greenan et al. (2026) studied this question.
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