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June 30, 2026Progress in Medical PhysicsOpen Access

Establishmet of Reproducible Ultra-High-Dose Rate Proton Beams Based on a Clinical Cyclotron System

Chae-Eon Kim Sang‐il Pak Seonghoon Jeong Seohyeon An Chankyu Kim Jong Hwi Jeong Hak‐Soo Kim Young Kyung Lim Dongho Shin Yoonsun Chung Se Byeong Lee

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Key Points

The aim is to establish reproducible ultra-high-dose rate proton beams using a clinical cyclotron system for enhanced radiation therapy applications.
Utilized a clinical cyclotron system to generate ultra-high-dose rate proton beams.
Conducted experiments to validate reproducibility and effectiveness in therapeutic settings.
Analyzed the dose distribution and impact on various tissue types during treatment simulations.
Proton beams demonstrated significant improvements in targeted dose delivery, achieving ultra-high-dose rates.
Validated reproducibility of the beam profiles over multiple sessions, with minimal variance in output.
Indicated potential for improved treatment efficacy in clinical applications of radiation therapy.

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Implication

Examines the effectiveness of ultra-high-dose rate proton beams in enhancing radiation therapy, suggesting improved treatment outcomes.

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Cite This Study

Kim et al. (2026) studied this question.

synapsesocial.com/papers/6a45ff6f9ed134303130fcd9 https://doi.org/10.14316/pmp.2026.37.2.54

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Characterization of a low-energy cyclotron-based proton beam for preclinical radiobiological studiesOriginal Research · 2026
2Feasibility of proton ultra-high-dose-rate spatially fractionated radiotherapy system for preclinical experiments on a compact proton synchrocyclotronOriginal Research · 2026 · 1 citations
3Characterization of a Modified Clinical Linear Accelerator for Ultra-High Dose Rate Beam Delivery2024 · 9 citations
4Development and characterisation of a radiobiology proton beamline using radiochromic film dosimetryOriginal Research · 2026
5Development and Evaluation of a Proton Irradiation Setup for Radiobiological Studies Using Low-Energy Protons with a Polyenergetic Spectrum (0–5.5 MeV, Mean 4.1 MeV)Original Research · 2026

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