Functional and Angiographic Outcomes Following Surgical Revascularization in Pediatric Moyamoya Disease: A Single-Centre Cohort Study from Central Asia
Cohort study reports improved functional outcomes in pediatric moyamoya disease after surgical revascularization, suggesting the importance of collateral formation.
Key Points
This study aims to evaluate the functional and angiographic outcomes of surgical revascularization in pediatric patients with moyamoya disease.
Retrospective cohort study of 45 pediatric patients with moyamoya disease undergoing surgical revascularization from 2013 to 2025.
Functional outcomes assessed using the modified Rankin Scale; angiographic outcomes evaluated with the Matsushima grading system.
Analysis of associations between clinical, surgical, and radiological factors and functional outcomes was performed.
Mean modified Rankin Scale (mRS) decreased from 2.09 ± 1.26 to 1.64 ± 1.00 (p = 0.004) following surgery.
82.2% of patients achieved favorable outcomes (mRS 1–2) at follow-up.
Postoperative collateral formation was strongly associated with functional outcomes (p = 0.005).