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August 1, 1979Journal of Biological ChemistryOpen Access

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine).

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Authors

OGOwen W. GriffithChildren's Hospital of WisconsinAMA MeisterMerck & Co., Inc., Rahway, NJ, USA (United States)

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Griffith et al. (1979) studied this question.

synapsesocial.com/papers/6a46fcbcc4ea4d05b84dad54https://doi.org/10.1016/s0021-9258(18)35980-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1New synthesis of S-alkyl- DL -homocysteines1969 · 16 citations
  2. 2Action of nitrogen trichloride on certain proteins II. Synthesis of methionine sulphoximine and other sulphoximines1951 · 47 citations
  3. 3Studies on the Synthesis of Amino Acids by the Schmidt Reaction. VI. Synthesis of Methionine Sulfoximine Analogs1960 · 6 citations
  4. 4Differential inhibition of glutamine and gamma-glutamylcysteine synthetases by alpha-alkyl analogs of methionine sulfoximine that induce convulsions.1978 · 101 citations
  5. 5Identification of L-methionine S-sulfoximine as the diastereoisomer of L-methionine SR-sulfoximine that inhibits glutamine synthetase1969 · 166 citations