Key result
A previous history of venous thromboembolism was the strongest independent risk factor for developing postoperative VTE following surgical treatment of fractures below the hip (RR 5.25).
Why the study?
What are the risk factors for developing VTE in patients undergoing surgery for fractures below the hip?
Population
191,294 patients from 23 cohort or case-control studies who underwent surgery for fractures below the hip.
Comparison
Presence of various clinical and procedural risk… vs Absence of the respective risk factors.
Design
Meta-analysis
Authors
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May support VTE risk stratification after hip fracture surgery; leaves open efficacy of tailored prophylaxis in high-risk subgroups.
Meta-Analysis (n=191,294)
What are the risk factors for developing VTE in patients undergoing surgery for fractures below the hip?
Relative Risk: 5.25 (95% CI 2.77–9.96)
p-value: p=0.000
Multiple patient-specific and procedural risk factors, notably previous VTE and varicose veins, significantly increase the risk of VTE after surgery for fractures below the hip, highlighting the need for targeted preventive strategies.
Tan et al. (2016) conducted a meta-analysis in Fractures below the hip requiring surgical treatment (n=191,294). Previous venous thromboembolism (VTE) vs. No previous history of VTE was evaluated on Development of postoperative venous thromboembolism (VTE) (RR 5.25, 95% CI 2.77-9.96, p=0.000). A previous history of venous thromboembolism was the strongest independent risk factor for developing postoperative VTE following surgical treatment of fractures below the hip (RR 5.25).
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