Key result
IVUS, OCT, and angioscopy identify false lumen and medial disruption in SCAD-induced acute MI.
Why the study?
Diagnosing spontaneous coronary artery dissection solely based on angiographic findings is often challenging, frequently requiring intravascular imaging modalities.
Case Report (n=1)
Comprehensive multimodality intravascular imaging, including angioscopy, can provide unprecedented details of SCAD and suggests a potential pathophysiological link with atherosclerosis.
Multimodality intravascular imaging may aid SCAD diagnosis in AMI; leaves open atherosclerosis link in this single case.
Spontaneous coronary artery dissection (SCAD) is a rare but critical cause of acute myocardial infarction (AMI). Diagnosing SCAD solely based on angiographic findings is often challenging; therefore, intravascular imaging modalities such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are often required. Angioscopy allows for direct visualization of the vascular lumen, enabling detailed assessment. Herein, we present a unique case of a young man who presented with AMI. Coronary angiography (CAG) revealed diffuse stenosis in the first septal branch; therefore, IVUS, OCT, and angioscopy were performed to obtain images with unprecedented details to evaluate the dissected cavity. Consequently, SCAD was confirmed owing to the identification of a dissected false lumen and a medial layer disruption. Mild atherosclerotic lesions were observed on coronary angioscopy. SCAD has traditionally been considered unrelated to atherosclerosis; however, our findings may indicate a potential pathophysiological link. This comprehensive imaging approach highlights the potential to improve the understanding of SCAD. This is the first case in which the dissection entry of SCAD was observed in detail using angiography.
No takes yet. Share an insight, caveat, or question.
Mori et al. (2025) conducted a case report in Acute Myocardial Infarction caused by Spontaneous Coronary Artery Dissection (n=1). Intravascular imaging (IVUS, OCT, and angioscopy) was evaluated. Intravascular imaging using IVUS, OCT, and angioscopy successfully identified a dissected false lumen and medial layer disruption in a young man with SCAD-induced acute myocardial infarction.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: