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April 1, 2022International Journal of Sports Physical TherapyOpen Access

Side Effects and Patient Tolerance with the Use of Blood Flow Restriction Training after ACL Reconstruction in Adolescents: A Pilot Study

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Key result

Blood flow restriction training was safe and well-tolerated in adolescents after ACL reconstruction, with 0% major adverse events and 10.47% of sessions unable to be completed due to tolerance.

Why the study?

While the effectiveness and safety of blood flow restriction training is established in healthy adults, data regarding patient tolerance and side effects during ACL reconstruction rehabilitation in adolescents remain limited.

Does blood flow restriction training have an acceptable safety and tolerance profile in adolescents following ACL reconstruction?

Population

29 adolescent patients aged 12 to 18 years after ACL reconstruction

Comparison

Standardized blood flow restriction training protocol

Design

Prospective cohort study

Follow-up

12 weeks

Authors

JPJennifer PrueDRDylan P. RomanNGNicholas Giampetruzzi

Discussion

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Member takes

Overview

BFRT showed low minor side effects without DVT in this adolescent ACL cohort; hypothesis-generating and requires RCTs before practice change.

Study Design

Type

Cohort (n=29)

Multicenter

No

Structured PICO

Does blood flow restriction training have an acceptable safety and tolerance profile in adolescents following ACL reconstruction?

P
Population
29 adolescents (mean age 15.4 years, 52% female) who underwent primary ACL reconstruction, followed over a 12-week early rehabilitation phase.
I
Intervention
Blood flow restriction training (BFRT) using an automatic personalized tourniquet system and standardized exercise protocol over 12 weeks starting 8.72 ± 3.32 days post-op.
O
Outcome
Reported side effects and patient tolerance to BFRT during ACLR rehabilitationsafety

Blood flow restriction training demonstrates a positive safety profile and good tolerance in adolescents undergoing rehabilitation after ACL reconstruction.

Limitations

  • Relatively small sample size of only 29 participants
  • Younger adolescent population was not equally represented
  • Patient intolerance may have been overestimated by defining 'inability to finish' as voluntary stoppage or inability to complete all 75 repetitions in eight minutes
  • Failure to capture long term side effects like delayed onset muscle soreness (DOMS)
  • small sample size

Cite This Study

Prue et al. (2022) conducted a cohort in Anterior Cruciate Ligament Reconstruction (ACLR) (n=29). Blood Flow Restriction Training (BFRT) was evaluated on Major adverse events (subcutaneous hemorrhage, deep vein thrombosis, fainting). Blood flow restriction training was safe and well-tolerated in adolescents after ACL reconstruction, with 0% major adverse events and 10.47% of sessions unable to be completed due to tolerance.

synapsesocial.com/papers/6a46fda88dd8ee62990509cbhttps://doi.org/10.26603/001c.32479
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Return to the Preinjury Level of Competitive Sport After Anterior Cruciate Ligament Reconstruction Surgery2010 · 632 citations
  2. 2The Effects of Restriction Pressures on the Acute Responses to Blood Flow Restriction Exercise2019 · 84 citations
  3. 3Relative safety of 4 weeks of blood flow‐restricted resistance exercise in young, healthy adults2010 · 235 citations
  4. 4Understanding the pathophysiology of itch2013 · 74 citations
  5. 5The Intriguing Role of Histamine in Exercise Responses2016 · 45 citations