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Pilot trial evaluates ulipristal acetate's effectiveness for managing early pregnancy loss, indicating a feasible alternative to mifepristone.
Mifepristone availability for medical management of early pregnancy loss (EPL) is limited in some settings. We report a single site, single arm pilot of ulipristal acetate for EPL management as an alternative to mifepristone. While recruitment was challenging, all participants adhered to study protocol and passed their pregnancy without additional intervention. Trial registration ClinicalTrials.gov (ID NCT05216952), registered January 19, 2022, https//clinicaltrials.gov/study/NCT05216952.
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Hagey et al. (2026) studied this question.
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