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This review aims to systematically characterize and validate the pharmaceutico-analytical methodologies and evaluations of Rajata Bhasma.

July 3, 2026Open Access

Critical Review of Rajata Bhasma (Incinerated Silver)

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This review aims to systematically characterize and validate the pharmaceutico-analytical methodologies and evaluations of Rajata Bhasma.
Academic database screening for literature on Rajata Bhasma
Evaluation of traditional processing (Shodhana, Marana)
Analysis of pre-clinical and clinical studies regarding toxicity and antimicrobial effects.
Rajata Bhasma is converted into nanoparticles (10-400 nm) primarily as bio-compatible silver sulfide and silver oxide.
Demonstrated broad-spectrum antimicrobial properties in pre-clinical bio-assays.
Non-toxic profiles were observed, including safety at under 5 μg/ml in zebrafish embryo assays.

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Critical review synthesizes pharmaceutico-analytical evaluations of Rajata Bhasma, indicating its safety and efficacy.

Dr. Pravin M. Tate2 Dr. Vidyawati P. Mathpati*1 (2026) studied this question.

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