Key result
Polypharmacy raises adverse drug reaction risk in older HF patients, warranting multidisciplinary deprescribing reviews.
Why the study?
Increasing HF treatment options and guideline adherence contribute to polypharmacy in older adults, highlighting limitations in international guidance for this population.
Integrating geriatricians and pharmacists into heart failure multidisciplinary teams can help manage the significant risks of polypharmacy in older, multimorbid adults.
May support deprescribing protocols in older HF patients; leaves open optimal multidisciplinary team composition and implementation.
Heart failure (HF) is a common health condition that typically affects older adults. Many people with HF are cared for on an inpatient basis, by noncardiologists, such as acute medical physicians, geriatricians and other physicians. Treatment options for HF are ever increasing, and adherence to guidelines for prognostic therapy contributes to polypharmacy, which is very familiar to clinicians who care for older people. This article explores the recent trials in both HF with reduced ejection fraction and HF with preserved ejection fraction and the limitations of international guidance in their management with respect to older people. In addition, this article discusses the challenge of managing polypharmacy in those with advanced age, and the importance of involving a geriatrician and pharmacist in the HF multidisciplinary team to provide a holistic and person-centred approach to optimisation of HF therapies.
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Stefil et al. (2022) conducted a review in Heart failure with polypharmacy. Multidisciplinary team management and deprescribing was evaluated. Polypharmacy in older adults with heart failure increases the risk of adverse drug reactions, highlighting the need for comprehensive medication reviews and deprescribing by a multidisciplinary team.
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