Key result
Over 10 years of intensive lipid therapy, coronary collateral flow capacity increased by 214% (P=0.009), with greater increases in patients whose angina disappeared (+331% vs +4%; P=0.05).
Why the study?
Does intensive lipid therapy improve coronary collateral diameter and flow capacity in patients with occluded arteries?
Population
13 patients with 17 occluded arteries
Design
Cohort
Follow-up
10 years
Authors
Loading...
Intensive lipid therapy was associated with collateral growth over 10 years; leaves open whether randomized trials will confirm clinical benefit.
Cohort (n=13)
Does intensive lipid therapy improve coronary collateral diameter and flow capacity in patients with occluded arteries?
p-value: p=0.009
A novel cineangiographic method demonstrates that 10 years of intensive lipid therapy is associated with significant growth in coronary collateral flow capacity, which correlates with the disappearance of angina.
Rockstroh et al. (2002) conducted a cohort in Occluded coronary arteries (n=13). Intensive lipid therapy vs. Pretreatment baseline was evaluated on Mean increase in estimated flow capacity (p=0.009). Over 10 years of intensive lipid therapy, coronary collateral flow capacity increased by 214% (P=0.009), with greater increases in patients whose angina disappeared (+331% vs +4%; P=0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: