Characterization of APOBEC expression and its correlation with clinical outcomes in cervical cancer, suggesting implications for HPV subtype influence.
The apolipoprotein B mRNA editing enzyme catalytic polypeptide-like (APOBEC) family links antiviral defense to cancer-associated mutagenesis, yet its immune-associated role in cervical cancer (CC) remains insufficiently understood. We aimed to characterize APOBEC expression patterns in CC in relation to HPV subtype, clinical outcome, interferon (IFN) signaling, and tumor immune microenvironment.
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Steger et al. (2026) studied this question.
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