Asymmetric Hydrophosphination of Quinolinones and Chromones Catalyzed by Chiral Phosphoric Acid

Here, we report the first highly efficient and enantioselective hydrophosphination of quinolinones and chromones catalyzed by chiral phosphoric acids, affording C2-stereogenic phosphorus derivatives in good yields and high enantioselectivities. Notably, these products serve as versatile synthetic intermediates that can be readily elaborated to a range of valuable phosphorus-containing molecules.