Key result
Real-time IVUS guidance enables successful true lumen wiring during PCI for SCAD.
Why the study?
PCI for SCAD has higher failure rates than atherosclerotic PCI primarily due to false lumen wiring, and the optimal wiring technique remains undefined.
Does real-time side-branch IVUS-guided wiring enable successful true lumen identification during PCI for spontaneous coronary artery dissection?
Case Report (n=1)
Does real-time side-branch IVUS-guided wiring enable successful true lumen identification during PCI for spontaneous coronary artery dissection?
Real-time side-branch IVUS can be used to guide accurate true lumen wiring during PCI for spontaneous coronary artery dissection.
BACKGROUND: Spontaneous coronary artery dissection (SCAD) causes acute coronary syndrome, particularly in younger patients without traditional risk factors. Percutaneous coronary intervention (PCI) for SCAD has higher failure rates than atherosclerotic PCI, primarily due to false lumen wiring. Intravascular ultrasound (IVUS) improves safety, but the optimal wiring technique is undefined. CASE SUMMARY: A 49-year-old woman with no cardiovascular risk factors presented with unstable angina. Imaging showed proximal subtotal occlusion of the right coronary artery with TIMI flow grade 2, consistent with SCAD. IVUS in the conus branch enabled successful guidewire advancement into the true lumen. DISCUSSION: This case illustrates a novel application of side-branch IVUS to guide true lumen wiring during SCAD PCI. TAKE-HOME MESSAGES: SCAD must be considered in patients without traditional risk factors presenting with acute coronary syndrome. PCI for SCAD carries a higher risk of iatrogenic dissection propagation, mandating intravascular imaging. Real-time IVUS-guided wiring enables accurate identification of the true lumen in SCAD.
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Elsherif et al. (2026) conducted a case report in Spontaneous coronary artery dissection (SCAD) (n=1). Real-time intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) was evaluated on Successful guidewire advancement into the true lumen. Real-time intravascular ultrasound-guided wiring enabled successful guidewire advancement into the true lumen during percutaneous coronary intervention for spontaneous coronary artery dissection.
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