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Observational cohort study assesses hereditary ovarian cancer presence in Belarusian women, indicating significant mutation detection need.
Between 15 and 25% of ovarian cancers (OC) are hereditary ovarian cancer (HOC) and are caused by high-penetrance mutations in the BRCA1 and BRCA2 genes. Methods such as PCR and NGS allow HOC to be detected in a larger number of patients. The aim of our study was to conduct cross-sectional testing of the OC-affected Belarusian female population for pathogenic mutations associated with the risk of HOC developing.
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Trukhan et al. (2026) studied this question.
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