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This study aimed to describe the distribution and frequency of SARS-CoV-2 lineages in healthcare settings in Brazil.

July 4, 2026Microbiology SpectrumOpen Access

Healthcare-facility-based SARS-CoV-2 genomic surveillance in Brazil: experience from the global action in healthcare network

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Randomized trial shows SARS-CoV-2 lineage dynamics in healthcare workers and inpatients, indicating a novel genomic approach.

This study aimed to describe the distribution and frequency of SARS-CoV-2 lineages in healthcare settings in Brazil.
Whole-genome sequencing of 993 samples from healthcare workers (75.4%) and inpatients (24.6%)
Analysis conducted between February 2023 and August 2024
Identified 113 distinct SARS-CoV-2 lineages across three distinct epidemic waves.
Majority lineages were XBB.1.5 and XBB.2.3 during the first wave, GK.1.1 and JD.1.1 in the second, and JN.1 and JN.1.9 in the third wave.
JN.1.9 showed significantly higher prevalence among healthcare workers compared to inpatients.
Co-infections with genetically distinct variants were identified, highlighting healthcare monitoring's relevance.

Brust et al. (2026) studied this question.

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