Key result
Diagnosis in the recent era (1993-2004) compared to 1973-1982 was associated with an increase in 5-year survival from 44% to 68% for localized Ewing sarcoma and 16% to 39% for metastatic disease.
Why the study?
What are the incidence and survival trends of Ewing sarcoma in patients aged 1 to 19 years over the past 3 decades?
Population
Patients 1 to 19 years of age diagnosed with Ewing sarcoma of the bone between 1973 and 2004 from the SEER…
Design
Cohort
Follow-up
up to 10 years
Authors
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Survival gains in pediatric Ewing sarcoma over 30 years may reflect treatment advances; leaves open identification of drivers in metastatic disease.
Observational
Yes
What are the incidence and survival trends of Ewing sarcoma in patients aged 1 to 19 years over the past 3 decades?
Absolute Event Rate: 68% vs 44%
Survival for both localized and metastatic Ewing sarcoma has clearly improved over the past 3 decades, though metastatic disease outcomes remain poor.
Esiashvili et al. (2008) conducted an observational in Ewing sarcoma of the bone. Diagnosis in recent era (1993-2004) vs. Diagnosis in earlier era (1973-1982) was evaluated on 5-year survival of localized disease. Diagnosis in the recent era (1993-2004) compared to 1973-1982 was associated with an increase in 5-year survival from 44% to 68% for localized Ewing sarcoma and 16% to 39% for metastatic disease.
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