Key result
A degree of stenosis superior to 50% in 3D printed coronary artery models created disturbed flows downstream of the contraction with an accented increase in wall shear stress at the stenosis throat.
Why the study?
Atherosclerosis progressively reduces blood supply to vital organs and remains a leading cause of death worldwide.
Experimental and numerical simulations in 3D printed models demonstrate that coronary stenosis >50% significantly alters downstream hemodynamics and increases wall shear stress.
Hypothesis-generating for coronary flow modeling; prospective in vivo validation needed before clinical adoption.
Atherosclerosis is a progressive disease that can significantly reduce blood supply to vital organs, being one of the main causes of death worldwide. In this work, a numerical and experimental study in 3D printed stenotic coronary arteries, considering both steady and pulsatile blood flow conditions, is presented. The results revealed that a degree of stenosis superior to 50% creates disturbed flows downstream of the contraction, with an accented increase in the wall shear stress measurements at the stenosis throat. Finally, the multiphase mixture was investigated and compared with a single-phase modelling, and only slight differences were observed right after the stenosis throat.
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Carvalho et al. (2020) studied Atherosclerosis. Degree of stenosis superior to 50% was evaluated on Hemodynamic changes (disturbed flows and wall shear stress). A degree of stenosis superior to 50% in 3D printed coronary artery models created disturbed flows downstream of the contraction with an accented increase in wall shear stress at the stenosis throat.
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