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January 1, 2021AnaesthesiaOpen Access

Fundamentals and innovations in regional anaesthesia for infants and children

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Key result

Recent innovations in pediatric regional anesthesia, including advanced peripheral nerve blocks and revived spinal techniques, offer safe and effective opioid-sparing analgesia.

Design

Review

Authors

GHGrant HeydingerNationwide Children's HospitalJTJoseph D. TobiasArkansas Children's HospitalGVGiorgio VenezianoNationwide Children's Hospital

Discussion

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Implication

Advanced peripheral blocks may expand opioid-sparing options in children; leaves open comparative efficacy and safety versus established techniques.

Structured PICO

P
Population
Infants and children requiring anaesthesia
I
Intervention
Regional anaesthesia techniques (including advanced peripheral nerve blocks, infant spinal anaesthesia, combined spinal/epidural techniques, and continuous 2-chloroprocaine infusions)

Regional anaesthesia techniques in children are evolving with advanced peripheral nerve blocks and a revival of infant spinal anaesthesia, offering safe opioid-sparing analgesia.

Limitations

  • The rarity of complications makes comparative analyses difficult.
  • Data cannot support the safety of one technique over the other regarding the site of epidural insertion in infants.

Cite This Study

Heydinger et al. (2021) conducted a review in Regional anaesthesia in infants and children. Regional anaesthesia techniques was evaluated. Recent innovations in pediatric regional anesthesia, including advanced peripheral nerve blocks and revived spinal techniques, offer safe and effective opioid-sparing analgesia.

synapsesocial.com/papers/6a49a04bbf54f04e123b4635https://doi.org/10.1111/anae.15283
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epidemiology and Morbidity of Regional Anesthesia in Children1996 · 531 citations
  2. 2The European society of regional anesthesia and pain therapy and the American society of regional anesthesia and pain medicine joint committee practice advisory on controversial topics in pediatric regional anesthesia I and II2017 · 60 citations
  3. 3The Third American Society of Regional Anesthesia and Pain Medicine Practice Advisory on Local Anesthetic Systemic Toxicity2018 · 479 citations
  4. 4Plasma Concentrations of Bupivacaine in Neonates After Continuous Epidural Infusion1997 · 96 citations
  5. 5The Mitochondrial Pathway of Anesthetic Isoflurane-induced Apoptosis2009 · 203 citations