Key result
Atrial extrastimulus pacing reveals ~47% longer SVC-RA slow or conduction block lines than sinus rhythm.
Why the study?
Diagonal conduction block lines at the electrophysiologically defined SVC-RA junction are not always observed, often requiring a conventional horizontal isolation approach.
Does high-resolution mapping with atrial extrastimulus pacing improve visualization of the SVC-RA junction compared to sinus rhythm mapping in patients undergoing electrophysiological mapping?
Observational (n=25)
Does high-resolution mapping with atrial extrastimulus pacing improve visualization of the SVC-RA junction compared to sinus rhythm mapping in patients undergoing electrophysiological mapping?
High-resolution mapping with atrial extrastimulus pacing significantly improves the visualization of the SVC-RA junction compared to sinus rhythm mapping, potentially facilitating superior vena cava isolation.
High-resolution extrastimulus mapping delineates longer SVC-RA block lines; leaves open whether it improves isolation durability or outcomes.
BACKGROUND: Recent studies have identified diagonal conduction block lines at the electrophysiologically defined superior vena cava (SVC)-right atrium (RA) junction using three-dimensional mapping systems and reported the utility of SVCI using these lines. However, these block lines are not always observed, requiring the use of a conventional horizontal isolation approach. OBJECTIVE: This study aimed to visualize the electrophysiologically defined SVC-RA junction using high-resolution mapping with atrial extrastimulus pacing. METHODS: Twenty-five patients underwent high-resolution mapping during sinus rhythm (Sinus map) and extrastimulus pacing (S2 map) using a three-dimensional mapping system (CARTO 3, version 8). Slow conduction or conduction block along the SVC-RA junction was assessed by adjusting the lower threshold cut-off value in the "early meets late" analysis. The length of slow or conduction block lines was compared between the two maps. RESULTS: The S2 map revealed significantly longer slow or conduction block lines compared to the Sinus map (52.5 ± 18.0 mm vs. 35.6 ± 16.1 mm, p = 0.0013). The adjusted lower threshold values were comparable between the two maps: 26.4 ± 3.7% for the S2 map and 25.2 ± 3.8% for the Sinus map (p = 0.2819). In the S2 map, a slow or block line covering more than half of the junction was observed in all patients. Furthermore, the sinus node was consistently located inferior to this line. CONCLUSION: High-resolution mapping with atrial extrastimulus pacing more clearly visualizes the SVC-RA junction, potentially enabling more effective SVCI and estimation of the sinus node location.
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Ishikura et al. (2025) conducted an observational in Patients undergoing electrophysiological mapping (n=25). High-resolution mapping with atrial extrastimulus pacing (S2 map) vs. High-resolution mapping during sinus rhythm (Sinus map) was evaluated on Length of slow or conduction block lines (p=0.0013). High-resolution mapping with atrial extrastimulus pacing revealed significantly longer slow or conduction block lines at the SVC-RA junction than sinus rhythm mapping (52.5 vs 35.6 mm, p=0.0013).
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