Key result
Mechanical aspiration with a stent-free strategy maintains vessel patency at 1 year in plaque erosion STEMI.
Why the study?
Does mechanical thrombus aspiration and a stent-free approach prevent adverse events in young STEMI patients with plaque erosion?
Case Report (n=1)
No
Does mechanical thrombus aspiration and a stent-free approach prevent adverse events in young STEMI patients with plaque erosion?
An imaging-guided, stent-free approach using mechanical thrombus aspiration may be feasible and safe in selected young STEMI patients with plaque erosion.
May support stent-free strategy in selected plaque erosion STEMI; hypothesis-generating and requires prospective trials before adoption.
A 34-year-old man with no cardiovascular history presented with anterior ST-elevation myocardial infarction and a large thrombotic occlusion of the mid left anterior descending artery. Following potent antithrombotic therapy and mechanical thrombus aspiration, angiography revealed vessel patency without residual significant stenosis, allowing a deferred stent strategy. Subsequent optical coherence tomography confirmed definite plaque erosion, supporting conservative management with dual antiplatelet and intensive lipid-lowering therapy. At 1-year follow-up, the patient remained asymptomatic with no adverse events, underscoring the feasibility of an imaging-guided, stent-free approach in selected young patients with erosion-related acute coronary syndromes.
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Castiello et al. (2026) conducted a case report in Anterior STEMI with plaque erosion (n=1). Mechanical thrombus aspiration and stent-free approach was evaluated on Clinical status and vessel patency at 1 year. Mechanical thrombus aspiration followed by a stent-free approach maintained vessel patency and resulted in no adverse events at 1 year in a young STEMI patient with plaque erosion.
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