Key result
Over 25 thrombus aspirations with deferred stenting demonstrates feasibility for resistant STEMI thrombus.
Why the study?
Stent placement in acute myocardial infarction with high thrombus load increases distal embolization risk, whereas deferred stenting with thrombus aspiration may completely remove thrombus and eliminate the need for stenting.
Does multiple thrombus aspiration attempts with deferred stenting improve TIMI flow and eliminate the need for stenting in a patient with late presentation STEMI and large resistant thrombus load?
Case Report (n=1)
Does multiple thrombus aspiration attempts with deferred stenting improve TIMI flow and eliminate the need for stenting in a patient with late presentation STEMI and large resistant thrombus load?
In a young patient with late-presenting STEMI and high thrombus burden, multiple aspiration attempts and deferred stenting may be a feasible strategy to avoid permanent stent placement.
Acute myocardial infarction is caused by the rupture or erosion of an atherosclerotic plaque, initiating intra-luminal thrombosis resulting in partial or complete occlusion of a coronary artery. Primary percutaneous coronary intervention (PCI) is the preferred treatment and is effective in opening the infarct-related artery. These results can be further improved with thrombus aspiration which reduces stent thrombosis and improves myocardial blush. In acute presentation, there is a high load of thrombus in the infarct-related artery and stent placement in such a case increases the chances of the thrombus shifting both proximally and distally in the microvasculature. In such patient, deferred stenting along with the attempt of thrombus aspiration has the potential for complete thrombus removal with improvement in TIMI flow which eliminates the need of stenting. Here, we present an interesting case report pertaining to the feasibility of multiple thrombus aspiration attempts (>25) as first approach in young patient (Male/32 years/no co-morbidities) with late presentation of STEMI and a large resistant thrombus load on an angiogram. We also re-assessed the need of stenting after 5 days of thrombus aspiration attempt along with continued anticoagulation from the first contact with patient.
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Tamakuwala et al. (2022) conducted a case report in Acute myocardial infarction (STEMI) (n=1). Multiple thrombus aspiration attempts (>25) and deferred stenting was evaluated on Feasibility of multiple thrombus aspiration attempts and need of stenting. Multiple thrombus aspiration attempts (>25) combined with deferred stenting was a feasible first-line approach for a large resistant thrombus in a 32-year-old male with STEMI.
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