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July 5, 2026BMC GeriatricsOpen Access

Community-based chest X-ray screening versus symptom-based case presentation in the elderly: evidence from three consecutive years of data

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Authors

KLKui LiuChinese Center For Disease Control and PreventionZFZiyang FangNingbo UniversityBCB ChenZhejiang Center for Disease Control and Prevention

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Implication

Randomized trial compares community-based chest X-ray screening to symptom-driven detection for tuberculosis in elderly populations, highlighting effective strategies.

Key Points

  • The aim is to compare community-based chest X-ray (CXR) screening and symptom-driven case detection for tuberculosis in individuals over 60 years.
  • Conducted three annual rounds of mass CXR screening in individuals aged over 60 years in Lanxi City, China, from 2021 to 2023.
  • Utilized restricted cubic spline and multivariable logistic regression analyses to assess detection pathways.
  • Identified a total of 831 tuberculosis cases through both screening methods.
  • CXR mass screening detected more patients with atypical symptoms compared to symptom-driven detection.
  • Significant effectiveness of symptom-driven detection in females (aOR = 0.59, 95% CI 0.39–0.88) and bacteriologically confirmed cases (aOR = 0.42, 95% CI 0.27–0.63).
  • CXR screening was initially more effective but showed declining effectiveness by the third round, with specific benefits for individuals with prior tuberculosis history.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6a49f591f5d1d45b288006fehttps://doi.org/10.1186/s12877-026-07931-8
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