Key result
BUN/Cr ratio >16.23 is linked to markedly higher MACE rates following acute myocardial infarction.
Why the study?
Risk stratification in acute myocardial infarction remains challenging, creating a need for simple, accessible indicators like the blood urea nitrogen to creatinine ratio.
Does an elevated BUN/Cr ratio (>16.23) predict rehospitalization and MACE in patients with acute myocardial infarction?
Cohort
No
Does an elevated BUN/Cr ratio (>16.23) predict rehospitalization and MACE in patients with acute myocardial infarction?
p-value: p=< 0.05
An elevated BUN/Cr ratio (>16.23) at admission serves as a simple, accessible prognostic marker for increased risk of major adverse cardiac events in patients with acute myocardial infarction.
BUN/Cr ratio was associated with post-AMI rehospitalization; leaves open its role in risk stratification pending prospective validation.
BACKGROUND: Risk stratification in acute myocardial infarction (AMI) remains a critical challenge in clinical practice. Traditional prognostic markers often require complex or costly assessments, underscoring the need for simple, accessible indicators. This study, conducted with the aim of evaluating the relationship between the blood urea nitrogen (BUN) and creatinine (Cr) ratio and rehospitalization following AMI. METHODS: This retrospective cohort study, conducted at a single center, patients diagnosed with AMI. BUN and Cr levels at the time of initial admission were collected to calculate the BUN/Cr ratio, which was categorized into two groups: ≤16.23 and >16.23. Statistical analyses were carried out using IBM SPSS software (version 22). RESULTS: < 0.05). CONCLUSION: While rehospitalization rates over a four‑year period were slightly higher among those with elevated ratios, the difference was not statistically significant. However, patients with a BUN/Cr ratio >16.23 demonstrated markedly increased rates of major adverse cardiac events (MACE) compared to those with lower ratios.
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Ebrahimi et al. (2026) conducted a cohort in Acute myocardial infarction (AMI). Blood urea nitrogen to creatinine (BUN/Cr) ratio >16.23 vs. BUN/Cr ratio ≤16.23 was evaluated on Rehospitalization (p=< 0.05). A BUN/Cr ratio >16.23 was associated with markedly increased rates of major adverse cardiac events compared to lower ratios in patients with acute myocardial infarction.
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