What does this research mean for the field?

Lung ultrasound scores demonstrate strong diagnostic accuracy (pooled sensitivity 0.85, specificity 0.80) for predicting the need for surfactant therapy in preterm neonates with respiratory distress syndrome. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This review aims to assess the diagnostic accuracy of lung ultrasound (LUS) scores in predicting surfactant therapy needs for preterm neonates with respiratory distress syndrome (RDS).

July 5, 2026Scientific ReportsOpen Access

Lung ultrasound score for predicting surfactant therapy in preterm neonates with respiratory distress syndrome a systematic review and meta analysis

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Authors

PNPrithvi N. NayakManipal Academy of Higher Education PKPrasali KulalManipal Academy of Higher Education VJVennila JaganathanManipal Academy of Higher Education

Discussion

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Implication

Systematic review evaluates lung ultrasound effectiveness for surfactant requirement in preterm neonates, suggesting timely interventions.

Key Points

This review aims to assess the diagnostic accuracy of lung ultrasound (LUS) scores in predicting surfactant therapy needs for preterm neonates with respiratory distress syndrome (RDS).
Systematic review and meta-analysis of 18 studies involving 997 neonates
Analyses used a bivariate random-effects model
Measures included sensitivity, specificity, and diagnostic odds ratio (DOR) for LUS scores.
Pooled sensitivity of LUS score was 0.85 (95% CI: 0.83–0.87) and specificity was 0.80 (95% CI: 0.77–0.82)
The DOR was 32.12 (95% CI: 18.99–54.33), indicating strong discriminatory ability
Different cutoff values for LUS scores showed varying sensitivity and specificity for surfactant prediction.

Cite This Study

Nayak et al. (2026) studied this question.

synapsesocial.com/papers/6a49f68df5d1d45b28800d53 https://doi.org/10.1038/s41598-026-60515-9

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Implication

Systematic review evaluates lung ultrasound effectiveness for surfactant requirement in preterm neonates, suggesting timely interventions.

Lung ultrasound score for predicting surfactant therapy in preterm neonates with respiratory distress syndrome a systematic review and meta analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Lung ultrasound score for predicting surfactant therapy in preterm neonates with respiratory distress syndrome a systematic review and meta analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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