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Maps immune aging and remodeling in adults, suggesting connections to disease risk.
A recent study by Gong et al. maps peripheral immune aging using multi-omic profiling and longitudinal influenza vaccination across adults aged 25-90+, revealing midlife (55-65) immune remodeling. Analyses of PBMCs, proteomics, and cell function show early dysregulation before aging, highlighting links to later disease susceptibility before inflammaging.
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Hicks et al. (2026) studied this question.
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