Retrospective study shows dual-source CT effectively assesses differentiation and serosal invasion in colorectal cancer, suggesting improved preoperative evaluation.
To evaluate the diagnostic efficacy of dual-source CT (DSCT) dual-energy technology in determining the differentiation degree and presence of serosal invasion in colorectal cancer (CRC), using normalized iodine concentration (NIC), electron density, and effective atomic number ( Z ) as diagnostic markers. A retrospective analysis was conducted on 102 patients clinically diagnosed and pathologically confirmed with CRC. Dual-energy images from both arterial and venous phases were obtained using third-generation DSCT. NIC values were computed. The study analyzed the diagnostic value of DSCT dual-energy technology, utilizing multiple parameters, in assessing the differentiation degree of CRC and the presence of serosal invasion. For differentiating high/moderate differentiation from low differentiation, the AUCs of NIC and Z were 0.899 and 0.914 in the arterial phase and 0.865 and 0.891 in the venous phase, respectively. For detecting serosal invasion, the arterial-phase AUCs of NIC and Z were 0.963 and 0.944, respectively, and the venous-phase AUC of NIC was 0.962. ρ showed no significant diagnostic value in these comparisons. DSCT dual-energy technology, through NIC and effective atomic number, offers significant diagnostic value for evaluating both the differentiation degree and serosal invasion in CRC, providing a novel approach for preoperative assessment.
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Wang et al. (2026) studied this question.
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