What is the clinical evidence from this study?

Study design: Cohort. Population: Non-cardiac surgery (n=5716). Intervention: Cardiovascular comorbidities. Primary outcome: Prevalence of cardiovascular comorbidities.

What does this research mean for the field?

Cardiovascular comorbidities are present in over 37% of non-cardiac surgery patients and frequently require perioperative management modifications, including surgical delays due to anticoagulation in 4.16% of cases. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

To assess the prevalence of cardiovascular comorbidities and evaluate their immediate impact on perioperative management in adult patients undergoing non-cardiac surgery.

July 5, 2026MedicinaOpen Access

Prevalence and Perioperative Implications of Cardiovascular Comorbidities in Non-Cardiac Surgery: A Three-Year Retrospective Cohort Study

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Key result

Cardiovascular comorbidities affect ~37% of non-cardiac surgery patients, led by hypertension.

n=5,716

Why the study?

Cardiovascular diseases are the leading cause of global morbidity and mortality and significantly influence perioperative risk in non-cardiac surgery, but their prevalence and immediate impact on perioperative management warranted evaluation.

Population

5716 adult patients undergoing elective or emergency non-cardiac surgery

Design

Retrospective cohort study

Authors

BGBogdan-Florin GodjeSpitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara SMSergiu-Ciprian MateiSpitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara AUAna‐Maria UngureanuSpitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara

Discussion

Member takes

Implication

Reinforces need for preoperative cardiovascular assessment before non-cardiac surgery; extends contemporary observational data supporting ESC guidelines.

Key Points

To assess the prevalence of cardiovascular comorbidities and evaluate their immediate impact on perioperative management in adult patients undergoing non-cardiac surgery.
Conducted a retrospective cohort study of N=5716 consecutive adult patients undergoing elective or emergency non-cardiac surgery at a tertiary surgical center between January 2022 and December 2024.
Analyzed demographic variables, primary surgical diagnoses, chronic medications, cardiovascular comorbidities, and documented perioperative pathway alterations using SPSS v16.
Cardiovascular comorbidities were present in 2157 patients (37.37%), with hypertension being the most common condition in 1908 patients (33.37%), followed by valvular heart disease (5.54%) and heart failure (5.19%).
Perioperative management was modified in approximately 5.9% of cases: surgery was delayed due to chronic anticoagulation in 238 patients (4.16%), postponed due to cardiovascular decompensation in 37 patients (1.27%), and contraindicated in 29 patients (0.50%).

Study Design

Type

Cohort (n=5,716)

Multicenter

Structured PICO

Population

5,716 adult patients (mean age 54.9 years, 48.2% female) undergoing elective or emergency non-cardiac surgery at a tertiary referral center in Romania between 2022 and 2024.

Outcome

Prevalence of cardiovascular comorbidities among patients undergoing non-cardiac surgery

Over one-third of patients undergoing non-cardiac surgery have cardiovascular comorbidities, which frequently necessitate modifications to perioperative management such as surgical delay or postponement.

Limitations

Retrospective design may introduce selection bias and limit the ability to establish causal relationships.
Conducted in a single tertiary center, which may affect generalizability.
Lack of postoperative outcomes and long-term follow-up data.
Reliance on medical records may have led to underreporting or misclassification of comorbidities.
Standardized variables such as ASA class and Revised Cardiac Risk Index were not consistently available for adjusted analyses.
Retrospective design may introduce selection bias and limit causal inferences
Single tertiary center limits generalizability
Lack of postoperative outcomes and long-term follow-up data
Reliance on medical records may lead to underreporting or misclassification
Lack of standardized variables (e.g., ASA class, RCRI) preventing adjusted analyses

Cite This Study

Godje et al. (2026) conducted a cohort in Non-cardiac surgery (n=5,716). Cardiovascular comorbidities was evaluated on Prevalence of cardiovascular comorbidities. Cardiovascular comorbidities were highly prevalent, affecting 37.37% of patients undergoing non-cardiac surgery, with hypertension being the most common condition (33.37%).

synapsesocial.com/papers/6a49f70df5d1d45b288011e1 https://doi.org/10.3390/medicina62071280

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Implication

Reinforces need for preoperative cardiovascular assessment before non-cardiac surgery; extends contemporary observational data supporting ESC guidelines.

Prevalence and Perioperative Implications of Cardiovascular Comorbidities in Non-Cardiac Surgery: A Three-Year Retrospective Cohort Study

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Limitations

Cite This Study

Prevalence and Perioperative Implications of Cardiovascular Comorbidities in Non-Cardiac Surgery: A Three-Year Retrospective Cohort Study

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider