Key result
Microvascular responsiveness of the lower limb remained unchanged between the early follicular and mid-luteal phases and the inactive- and active-pill phases of the oral contraceptive cycle (P=0.09).
Why the study?
It was unknown whether menstrual or monophasic oral contraceptive cycle phases affect lower limb microvascular responsiveness in healthy, active women.
Does the menstrual or oral contraceptive cycle phase affect microvascular responsiveness in healthy, active women?
Observational (n=30)
Does the menstrual or oral contraceptive cycle phase affect microvascular responsiveness in healthy, active women?
p-value: p=0.09
Controlling for menstrual or oral contraceptive cycle phases may not be necessary when assessing NIRS-VOT reperfusion rates in healthy women.
No takes yet. Share an insight, caveat, or question.
Cycle phase does not affect microvascular reperfusion in healthy women; leaves open whether control is needed in other populations or methods.
Mattu et al. (2019) conducted an observational in Healthy, active women (n=30). Menstrual and oral contraceptive cycle phases vs. Different cycle phases (follicular vs luteal; inactive vs active pill) was evaluated on Near-infrared spectroscopy-derived muscle oxygen saturation reperfusion slope and area under the curve (p=0.09). Microvascular responsiveness of the lower limb remained unchanged between the early follicular and mid-luteal phases and the inactive- and active-pill phases of the oral contraceptive cycle (P=0.09).
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