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December 1, 2013

Cardioversion in Acute Atrial Fibrillation Without Anticoagulation.

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Key result

Cardioversion of acute atrial fibrillation without anticoagulation carries a low risk of thromboembolic events in patients without risk factors, but a risk of approximately 10% in those with multiple risk factors.

Why the study?

Does cardioversion without anticoagulation increase the risk of thromboembolic events in patients with acute atrial fibrillation?

Population

Patients with acute atrial fibrillation (<48 hours) scheduled for cardioversion

Comparison

Cardioversion without anticoagulation vs Cardioversion with anticoagulation

Design

Review

Authors

JAJuhani AiraksinenElectrophysiologyWNWail NammasUniversity of TurkuINIlpo NuotioElectrophysiology

Discussion

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Implication

May support selective anticoagulation omission before acute AF cardioversion in low-risk patients; leaves open prospective validation in those with multiple risk factors.

Structured PICO

Does cardioversion without anticoagulation increase the risk of thromboembolic events in patients with acute atrial fibrillation?

P
Population
Patients with acute atrial fibrillation (<48 hours) scheduled for cardioversion
I
Intervention
Cardioversion without anticoagulation
C
Comparator
Cardioversion with anticoagulation (unfractionated or low-molecular weight heparin followed by oral anticoagulation)
O
Outcome
Thromboembolic eventshard clinical

Cardioversion of acute atrial fibrillation without anticoagulation is safe only in patients without stroke risk factors, while those with multiple risk factors face a high risk of thromboembolism and require anticoagulation.

Cite This Study

Airaksinen et al. (2013) conducted a review in Acute atrial fibrillation. Cardioversion without anticoagulation was evaluated on Thromboembolic events. Cardioversion of acute atrial fibrillation without anticoagulation carries a low risk of thromboembolic events in patients without risk factors, but a risk of approximately 10% in those with multiple risk factors.

synapsesocial.com/papers/6a4c4247028ea97264ab7671https://doi.org/10.4022/jafib.970
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Risk for Clinical Thromboembolism Associated with Conversion to Sinus Rhythm in Patients with Atrial Fibrillation Lasting Less Than 48 Hours1997 · 241 citations
  2. 2Thirty‐day Outcomes of Emergency Department Patients Undergoing Electrical Cardioversion for Atrial Fibrillation or Flutter2010 · 66 citations
  3. 3Management of Newly Detected Atrial Fibrillation: A Clinical Practice Guideline from the American Academy of Family Physicians and the American College of Physicians2003 · 148 citations