Cardiovascular Health Status in US Adults With Chronic Diseases: National Health and Nutrition Examination Survey (NHANES), 2013–2018
Key result
Chronic diseases linked to ~14-point lower LE8 scores versus healthy adults.
- MD -14.0
- P<0.0001
- n=12,296
Why the study?
Few studies have compared cardiovascular health between adults with chronic diseases and healthy adults without chronic disease using the AHA Life's Essential 8 metrics.
Does the presence of chronic diseases associate with lower cardiovascular health (Life's Essential 8 scores) in US adults?
Population
12 296 adults aged 20 to 79 years from NHANES 2013 to 2018
Comparison
Adults with chronic diseases vs unaffected adults
Design
Cross-sectional survey study
Authors
Discussion
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Member takes
Implication
LE8 scores are lower in COPD, signaling elevated CV risk; leaves open whether optimizing LE8 improves outcomes.
Study Design
Type
Cross-Sectional (n=12,296)
Multicenter
Yes
Structured PICO
Does the presence of chronic diseases associate with lower cardiovascular health (Life's Essential 8 scores) in US adults?
P
Population
12,296 US adults aged 20 to 79 years, representing >186 million noninstitutionalized adults, assessed for cardiovascular health using Life's Essential 8 metrics.
E
Exposure
Presence of chronic diseases (16 conditions studied)
C
Comparator
Healthy adults without chronic disease
O
Outcome
Overall mean Life's Essential 8 (LE8) score and individual LE8 metric scoressurrogate
Main Result
Mean Difference: -14
Absolute Event Rate: 51% vs 65%
p-value: p=<0.0001
Cardiovascular health, as measured by the AHA's Life's Essential 8 metrics, is significantly poorer in US adults with chronic diseases compared to unaffected adults, highlighting the need for targeted optimization.
Cite This Study
Guo et al. (2024) conducted a cross-sectional in Chronic diseases (n=12,296). Presence of chronic diseases vs. Unaffected adults (without chronic disease) was evaluated on Overall mean Life's Essential 8 (LE8) score (MD -14.0, p=<0.0001). Adults with chronic diseases, such as COPD, had significantly lower cardiovascular health scores compared with unaffected adults (mean LE8 score 51.0 vs 65.0, P<0.0001).