Key result
Pulmonary vein isolation using the fourth-generation cryoballoon was achieved in 100% of targeted veins, allowing time-to-isolation determination in 84.8% of veins.
Why the study?
Time-to-isolation guided ablation protocols ensure durable PVI in cryoballoon ablation, prompting evaluation of the feasibility and safety of the fourth-generation cryoballoon with a shortened tip.
Is the fourth generation cryoballoon with a shortened tip feasible and safe for pulmonary vein isolation in patients with atrial fibrillation?
Population
76 consecutive patients scheduled for initial AF ablation
Comparison
PVI with 28 mm fourth-generation cryoballoon and 20 mm spiral-mapping catheter
Design
Prospective cohort study
Authors
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Shortened-tip CBG4 supports TTI-guided PVI feasibility; leaves open durability and safety versus prior generations in larger trials.
Observational (n=76)
Is the fourth generation cryoballoon with a shortened tip feasible and safe for pulmonary vein isolation in patients with atrial fibrillation?
The fourth-generation cryoballoon with a shortened tip is feasible and safe for initial AF ablation, allowing real-time time-to-isolation determination in the vast majority of pulmonary veins.
Straube et al. (2019) conducted an observational in Atrial fibrillation (n=76). Fourth generation cryoballoon (CBG4) with a shortened tip was evaluated on Pulmonary vein isolation (PVI) achievement. Pulmonary vein isolation using the fourth-generation cryoballoon was achieved in 100% of targeted veins, allowing time-to-isolation determination in 84.8% of veins.
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