Key result
Reduced left ventricular ejection fraction remains the cornerstone of sudden cardiac death risk stratification, though emerging tools like ECG parameters, biomarkers, and imaging show prognostic value.
Why the study?
What are the current tools and evidence for risk stratification of sudden cardiac death across different patient populations?
What are the current tools and evidence for risk stratification of sudden cardiac death across different patient populations?
This review provides an overview of current and emerging tools for sudden cardiac death risk stratification across different patient populations.
Risk stratification beyond LVEF may miss most SCD events; leaves open need for broader tools in populations without known cardiac disease.
While various modalities to determine risk of sudden cardiac death (SCD) have been reported in clinical studies, currently reduced left ventricular ejection fraction remains the cornerstone of SCD risk stratification. However, the absolute burden of SCD is greatest amongst populations without known cardiac disease. In this review, we summarize the evidence behind current guidelines for implantable cardioverter defibrillator (ICD) use for the prevention of SCD in patients with ischemic heart disease (IHD). We also evaluate the evidence for risk stratification tools beyond clinical guidelines in the general population, patients with IHD, and patients with other known or suspected medical conditions.
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Ragupathi et al. (2014) conducted a review in Sudden cardiac death. Risk stratification tools was evaluated. Reduced left ventricular ejection fraction remains the cornerstone of sudden cardiac death risk stratification, though emerging tools like ECG parameters, biomarkers, and imaging show prognostic value.
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