The aim of this study was to compare three delivery methods of a hydraulic calcium silicate cement-based sealer by quantifying voids using the single-cone technique. Forty-eight human mandibular molars were instrumented and scanned using micro-computed tomography. The specimen's aspect ratio, shape, and volume were analysed to allow even distribution across three experimental groups (n = 16): sealer injection with a syringe, coating of the master cone and sealer injection followed by sonic agitation. Post-filling micro-computed scanning was used to quantify void volumes in each specimen. Statistical analysis using Kruskal-Wallis and Dunn's post hoc tests (α = 0.05) revealed no significant difference in void volume among the delivery methods (p = 0.120). However, canal shape was a significant factor; round canals exhibited significantly fewer voids than any other shape (p < 0.001). In conclusion, the delivery method did not influence the density of the root canal filling; canal anatomy was the more critical determinant factor for void formation.
Andreani et al. (Sun,) studied this question.