Comparison of Corneal Endothelial and Anterior Segment Changes After Nd:YAG Laser Capsulotomy in Eyes with and without Pseudoexfoliation Syndrome

PURPOSE: To compare the changes in corneal endothelium and anterior segment parameters following neodymium:yttrium-aluminum-garnet (Nd:YAG) laser capsulotomy in eyes with and without pseudoexfoliation syndrome (PEX). METHODS: Our study included 72 eyes with posterior capsular opacification (PCO). Patients were divided into two groups: PEX and control. All patients underwent detailed examination followed by Nd:YAG laser. Corneal endothelium was evaluated using specular microscopy, and anterior segment parameters were assessed using Sirius corneal topography before laser, at 1 week and 1 month post-laser. Findings were compared between PEX and control groups. RESULTS: = .246). No significant correlation was found between laser energy parameters and clinical variables. CONCLUSION: A significant decrease in ECD was observed in the PEX group after Nd:YAG laser, whereas this difference was not prominent in the control group. Our results suggest that evaluating ECD before Nd:YAG laser may help minimize potential endothelial damage, especially in patients with PEX.