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July 8, 2026PLoS ONEOpen Access

Barriers and facilitators to healthcare utilization amongst people living with sickle cell disease in the United States: A scoping review

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Authors

CRChristina RuanJGJoyce GyamfiNONana Osei-tutu

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Overview

Scoping review identifies barriers and facilitators influencing healthcare use in individuals with sickle cell disease in the U.S., urging for systemic changes.

Key Points

  • This review aims to identify barriers and facilitators impacting healthcare utilization among individuals living with sickle cell disease in the U.S.
  • Conducted a scoping review of literature on healthcare utilization for sickle cell disease in the U.S.
  • Screened 708 articles, with 70 meeting the inclusion criteria, from a systematic search of seven data sources.
  • Assessments included data extraction and risk of bias evaluation by two independent reviewers.
  • The most common barriers to healthcare utilization were social (25), interpersonal (23), economic (15), and institutional factors (11).
  • Major facilitators included technology (9), education (7), autonomy (6), and positive patient-provider relationships (6).
  • Evidence-based interventions decreasing healthcare avoidance: individualized pain plans (4) and quality improvement strategies (3).

Cite This Study

Ruan et al. (2026) studied this question.

synapsesocial.com/papers/6a4de8a7d2ea289ef6283383https://doi.org/10.1371/journal.pone.0349441
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Also Consider

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  5. 5Perceptions of Ethnic and Cultural Factors in the Delivery of Services in the Treatment of Sickle Cell Disease1994 · 15 citations